@article{oai:showa.repo.nii.ac.jp:00000643,
 author = {UMEMOTO, Takahiro and HARADA, Yoshikuni and SAKATA, Makiko and SAKURABA, Kazuma and MIZUKAMI, Hiroki and SAITO, Mitsuo and KIGAWA, Gaku and NEMOTO, Hiroshi and HIBI, Kenji},
 issue = {3},
 journal = {The Showa University journal of medical sciences},
 month = {2013-09, 2019-07-26},
 note = {A 79-year-old woman presented to our hospital with frequent episodes of hematochezia. Colonoscopy revealed an apparent tumor with central ulceration, and analysis of biopsy specimens confirmed the presence of non-invasive squamous cell carcinoma of the anal canal. No distant metastases were identified on enhanced computed tomography (CT). The cancer was classified as stage II (T2N0M0), and chemoradiotherapy (CRT) was selected as the first-line treatment. A continuous intravenous infusion of 5-fluorouracil with daily cisplatin was planned on days 1 to 5 of a 4-week cycle. After the first course, the drug administration was discontinued because the patient experienced diarrhea as an adverse event, and treatment with daily oral titanium silicate-1 (TS-1) was initiated. In addition, a total of 65Gy of radiation was applied to the primary lesion, pelvis, and bilateral groin area. Four weeks after the completion of CRT, colonoscopy showed the disappearance of the tumor and analysis of biopsy specimens confirmed the absence of any viable cancer cells. CT showed no evidence of lymph node metastasis or distant metastases. At 10 months after the completion of CRT, the patient showed no recurrence and with complete response.},
 pages = {243--248},
 title = {Chemoradiotherapy for Squamous Cell Carcinoma of the Anal Canal: A Case Report},
 volume = {25},
 year = {}
}