@article{oai:showa.repo.nii.ac.jp:00000573, author = {AOKI, Takeshi and MURAKAMI, Masahiko and KOIZUMI, Tomotake and ENAMI, Yuta and KOIKE, Reiko and FUJIMORI, Akira and KUSANO, Tomokazu and MATSUDA, Kazuhiro and YAMADA, Kosuke and NOGAKI, Koji and WADA, Yusuke and HAKOZAKI, Tomoki and TOMIOKA, Kodai and GOTO, Satoru and YOSHITAKE, Osamu and WATANABE, Makoto and OTSUKA, Koji}, issue = {3}, journal = {The Showa University journal of medical sciences}, month = {2015-09, 2019-07-26}, note = {The use of ultrasonically activated devices (USADs) in hepatic resections may be associated with an increased rate of complications, such as postoperative bile leaks. Nonetheless, the safety of USADs for sealing bile ducts during liver surgery has not yet been established. The purpose of this study was to assess the efficacy of a USAD for sealing bile ducts. In animal experiments, the common bile duct of ten anesthetized dogs was individually occluded using a USAD. Additionally, using the prospective liver surgery database from a single institution, we identified 45 consecutive patients who underwent hepatic resection using a USAD (USAD group) and 45 similar patients who underwent hepatic resection without the use of a USAD (NUSAD group). In the occluded and harvested canine bile ducts, the mean burst pressure was 280mmHg, and the lumen of the bile duct was completely sealed morphologically. In the clinical study, there was no significant difference in postoperative mortality or complications between the two groups, and biliary leakage was observed in only one patient (0.7%) in the USAD group. These data demonstrate that the USAD is a safe, efficient, and practical instrument for use during liver surgery to achieve complete hemobiliary stasis.}, pages = {185--192}, title = {Efficacy and Safety of an Ultrasonically Activated Device for Sealing the Bile Ducts During Liver Resection}, volume = {27}, year = {} }