{"created":"2023-05-15T11:21:48.493189+00:00","id":470,"links":{},"metadata":{"_buckets":{"deposit":"b219b0d8-0a37-4b6f-b235-a220761bc664"},"_deposit":{"created_by":1,"id":"470","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"470"},"status":"published"},"_oai":{"id":"oai:showa.repo.nii.ac.jp:00000470","sets":["1:51:56:58"]},"author_link":["2211","2210","2205","2212","2213","2206","2208","2214","2209","2204","2207"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-06"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"235","bibliographicPageStart":"227","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"The Showa University journal of medical sciences"}]}]},"item_10002_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Traditionally, cervical brachytherapy has been prescribed to point A. However, since the Groupe Europ?en de Curieth?rapie and European Society for Radiotherapy＆ Oncology guidelines were published, image-guided brachytherapy has become an emerging technique. The purpose of this study was to evaluate the high-risk clinical target volume （HR-CTV） coverage and analyze dose-volume histograms for organs at risk in point A prescription of high-dose-rate brachytherapy. A total of 68 patients with locally advanced cervical cancer were treated with three-dimensional conformal external beam radiation therapy and brachytherapy from December 2012 to March 2017. Fractions of 6Gy for a total of 12-24Gy were delivered at point A by brachytherapy to all patients. Following each brachytherapy application, a pelvic computed tomography scan was performed and imported into a three-dimensional brachytherapy treatment planning system. In this study, the HR-CTV, bladder, and rectum were re-delineated according to Report 89 of the International Commission on Radiation Units and Measurements using the magnetic resonance images at the time of diagnosis, and the dose-volume histogram of each structure was analyzed. The median age of patients at diagnosis was 67 years （range, 31-91 years）. Mean HR-CTV D90 for all patients was 558.3cGy （range, 228.7-1005.1cGy） and the mean HR-CTV D90 within each clinical T stage was: Ib, 646.4cGy; 2a, 579.3cGy; 2b, 545.2cGy; 3a, 556.6cGy; 3b, 451.3cGy; and 4, 497.9cGy. HR-CTVD90 was correlated with HR-CTV. The mean D2cm3 was 678.1cGy for the bladder and 511.9cGy for the rectum. Using point A-based dose prescription, HR-CTV coverage was insufficient, especially in cases with a large tumor volume or a high T stage. Image-guided brachytherapy is expected to improve HR-CTV coverage while keeping rectal and bladder doses within acceptable levels.","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Showa University Society"}]},"item_10002_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.15369/sujms.30.227"}}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0915-6380 "}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KOBAYASHI, Rei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KAGAMI, Yoshikazu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SHINJO, Hidenori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MURAKAMI, Kouzou"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MIYAURA, Kazunori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OZAWA, Yukiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KATO, Masako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NIIYA, Akifumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MATSUMOTO, Koji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MOROTA, Madoka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OKABE, Naoyuki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-26"}],"displaytype":"detail","filename":"S30_227.pdf","filesize":[{"value":"336.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"S30_227.pdf","url":"https://showa.repo.nii.ac.jp/record/470/files/S30_227.pdf"},"version_id":"810a17ba-11c5-4172-b973-860352ff8a6d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper"}]},"item_title":"Dose-Volume Histogram Analysis in Point A-based Dose Prescription of High-dose-rate Brachytherapy for Cervical Carcinoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Dose-Volume Histogram Analysis in Point A-based Dose Prescription of High-dose-rate Brachytherapy for Cervical Carcinoma"}]},"item_type_id":"10002","owner":"1","path":["58"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-09-03"},"publish_date":"2018-09-03","publish_status":"0","recid":"470","relation_version_is_last":true,"title":["Dose-Volume Histogram Analysis in Point A-based Dose Prescription of High-dose-rate Brachytherapy for Cervical Carcinoma"],"weko_creator_id":"1","weko_shared_id":1},"updated":"2023-05-15T12:46:10.668155+00:00"}