@article{oai:showa.repo.nii.ac.jp:00003378,
 author = {GOKAN, Toshihiko and KAWAMURA, Mitsuharu and ARAI, Shuhei and YOSHIKAWA, Kosuke and TANISAWA, Hiroki and OGAWA, Ko and OCHI, Akinori and ONISHI, Yoshimi and MUNETSUGU, Yumi and ITO, Hiroyuki and ONUKI, Tatsuya and KOBAYASHI, Youichi and SHINKE, Toshiro},
 issue = {1},
 journal = {The Showa University journal of medical sciences},
 month = {2020-04, 2020-06-02},
 note = {Survivors of ventricular fibrillation out-of-hospital cardiac arrest（VF-OHCA）due to potentially reversible causes such as acute coronary syndrome（ACS）, vasospastic angina and electrolyte abnormalities are considered low risk for recurrent arrhythmia. Accordingly, implantable cardioverter-defibrillator therapy is not routinely recommended in such patients. We investigated the risk of mortality and the value of ICD therapy for VF-OHCA. Among 2,248 cardiopulmonary arrest patients presenting at our hospital, we retrospectively investigated 110 patients with VF-OHCA who were admitted for treatment. We divided the patients based on ICD（n＝71） or No-ICD status（n＝39）, and on reversible cause（n＝70） or irreversible cause（n＝40）. The groups were compared for baseline characteristics, mortality and ICD therapies. Patients with a reversible cause had a significantly lower rate of ICD implantation than those with an irreversible cause（P＝0.03）. Males in the ICD group presented more frequently than those in the No-ICD group, and cardiac mortality in patients with acute coronary syndrome was significantly lower with ICD therapy than without ICD（P＝0.04）. The rate of appropriate ICD therapies with a reversible cause was 28％, and the first ICD therapy was highest within 1 year post-implantation. Patients with VF-OHCA due to a reversible cause remain at high risk of recurrent ventricular arrhythmias, suggesting that ICD implantation is a reasonable approach in such cases.},
 pages = {43--55},
 title = {Effect of Implantable Cardioverter-defibrillator Therapy for Ventricular Fibrillation Patients with Out-of-hospital Cardiac Arrest},
 volume = {32},
 year = {}
}