{"created":"2023-05-15T11:21:30.821523+00:00","id":176,"links":{},"metadata":{"_buckets":{"deposit":"5b34587d-b520-4d18-bc72-5f554054bdf5"},"_deposit":{"created_by":1,"id":"176","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"176"},"status":"published"},"_oai":{"id":"oai:showa.repo.nii.ac.jp:00000176","sets":["1:6:19:23"]},"author_link":["846","841","843","842","845","844"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-08"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"485","bibliographicPageStart":"480","bibliographicVolumeNumber":"76","bibliographic_titles":[{"bibliographic_title":"昭和学士会雑誌"}]}]},"item_10002_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"掌蹠膿疱症は原因不明の難治性疾患であるが，誘因として病巣感染，喫煙，金属アレルギー等が指摘されている．本症における金属アレルギーを検討する目的で，22年間のパッチテスト結果を検討した．1990年4月より2012年3月までに昭和大学病院附属東病院皮膚科を受診し，歯科金属シリーズのパッチテストを施行された1,025名 (男210名，女815名，4～85歳, 平均年齢40.1±18.1歳) を対象に，掌蹠膿疱症患者群 (148名) と他疾患患者群 (877名) との間で陽性率の比較を行った．パッチテストは18種類の金属試薬を健常皮膚に貼付し，48時間後に除去した．判定は72時間後にICDRG (International Contact Dermatitis Research Group) 基準に基づいて施行し，＋～＋＋＋を陽性とした．掌蹠膿疱症患者群と他疾患患者群とで金属の陽性率を比較すると，0.5%塩化白金酸に対する陽性率が前者では6.8% (148名中10名)であったのに対して，後者では2.6% (877名中23名) であり，χ2検定で両群間に有意差が認められた (p＜0.05)．したがって，掌蹠膿疱症においては白金(Pt)に対するアレルギー反応が重要な役割を担っている可能性が高いと考えられた．本症のパッチテスト結果について，1施設での長期間にわたるデータの検討結果は報告されておらず，新知見を与える研究と考えられる．","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"昭和大学学士会"}]},"item_10002_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.14930/jshowaunivsoc.76.480"}}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2187-719X"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"片山, 恵子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"伊藤, 雄太"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"濱田, 裕子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宇野, 裕和"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中田, 土起丈"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"末木, 博彦"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-26"}],"displaytype":"detail","filename":"76_480.pdf","filesize":[{"value":"342.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"76_480.pdf","url":"https://showa.repo.nii.ac.jp/record/176/files/76_480.pdf"},"version_id":"530a1b94-f107-4946-9f23-6b32ac5b7a02"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper"}]},"item_title":"掌蹠膿疱症における金属感作に関する検討 ","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"掌蹠膿疱症における金属感作に関する検討 "}]},"item_type_id":"10002","owner":"1","path":["23"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-05-15"},"publish_date":"2017-05-15","publish_status":"0","recid":"176","relation_version_is_last":true,"title":["掌蹠膿疱症における金属感作に関する検討 "],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T13:09:23.438735+00:00"}