WEKO3
アイテム
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Positive Relationship between L-type Amino Acid Transporter 1 Expression and Liver Metastasis in T3 Colorectal Cancer
https://showa.repo.nii.ac.jp/records/701
https://showa.repo.nii.ac.jp/records/701e4f3aa57-5a42-4369-8af7-2f4e5bcab9fb
名前 / ファイル | ライセンス | アクション |
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S23_145.pdf (252.8 kB)
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Item type | 学内発行雑誌 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-12-17 | |||||
タイトル | ||||||
タイトル | Positive Relationship between L-type Amino Acid Transporter 1 Expression and Liver Metastasis in T3 Colorectal Cancer | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ | departmental bulletin paper | |||||
著者 |
KATO, Kaoru
× KATO, Kaoru× KUNIMURA, Toshiaki× YOSHIDA, Tomohiko× TAKANO, Yuichi× H0B0, Takahiro× NOGAKI, Koji× HAMATANI, Shigeharu× MIKOGAMI, Tetsuya× OMATSU, Mutsuko× MOROHOSHI, Toshio |
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書誌情報 |
The Showa University journal of medical sciences 巻 23, 号 3, p. 145-151, 発行日 2011-09 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The aim of this retrospective study was to evaluate L-type amino acid transporter 1 (LAT1) expression in colorectal cancer with invasion to the subserosal layer (T3), its relationship with clinicopathological characteristics, and its potential metastatic significance. LAT1 expression was measured by immunohistochemistry in tumors from 65 patients with primary colorectal carcinomas. LAT1 expression was deemed positive when more than 10% of the tumor cells showed distinct membranous immunoreactivity. Positive LAT1 expression was demonstrated in 29.2% (19 of 65) of primary tumors. LAT1 expression showed no significant relationship with clinicopathological characteristics, such as age, gender, tumor location, tumor size, macroscopic/microscopic classification, or lymph node metastasis. However, LAT1 expression showed a positive relationship with liver metastasis (P < 0.05). LAT1 expression in cancer cells may be a good marker for predicting potential metastasis to the liver in colorectal cancer. | |||||
DOI | ||||||
関連識別子 | 10.15369/sujms.23.145 | |||||
出版者 | ||||||
出版者 | Showa Medical Association and Showa University | |||||
ISSN | ||||||
収録物識別子 | 0915-6380 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |