WEKO3
アイテム
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Urinary Myoinositol Index: A New and Better Marker for Postmeal Hyperglycemia
https://showa.repo.nii.ac.jp/records/690
https://showa.repo.nii.ac.jp/records/690427c9e10-a259-421b-bc1e-04b6ea862c33
名前 / ファイル | ライセンス | アクション |
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S24_33.pdf (439.5 kB)
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Item type | 学内発行雑誌 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-12-17 | |||||
タイトル | ||||||
タイトル | Urinary Myoinositol Index: A New and Better Marker for Postmeal Hyperglycemia | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ | departmental bulletin paper | |||||
著者 |
MIYAGI, Masahiko
× MIYAGI, Masahiko× KUBOKI, Koji× MATSUMOTO, Tomoko× ISO, Kaoru× MURAKAMI, Eiichi× YOSHINO, Gen |
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書誌情報 |
The Showa University journal of medical sciences 巻 24, 号 1, p. 33-41, 発行日 2012-03 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We investigated the usefulness of the urinary myoinositol index (UMI) for identifying postmeal hyperglycemia in type 2 diabetics undergoing a meal tolerance test. Fifty-eight patients (18 males, 40 females) were enrolled, fasted overnight and blood collected prior to and 1 and 2 hours following the test meal. Urine was collected 2 hours after the test meal. Plasma 1,5-anhydroglucitol (1,5-AG) was measured enzymatically, and UMI with an improved enzymatic cycling method. Simple and multiple regression analyses were employed to determine correlations between plasma glucose (PG) and three PG markers; HbA1C (Japan Diabetes Society), 1,5-AG and UMI. Study population characteristics were age 67.6±7.9 years, body mass index 24.9±3.8kg/m2 and waist circumference 90.2±10.4cm. Mean concentrations for PG were 130±23mg/dL (fasting), 179±46mg/dL (1h postmeal) and 150±49mg/dL (2h postmeal), HbA1C (6.3±0.6%), 1,5-AG (11.9±5.7μg/mL) and 2h UMI (52.0±35.9mg/gCr). Correlation coefficients were calculated between 1h postmeal PG and HbA1C (r=0.558), 1,5-AG (r=0.256), and 2h UMI (r=0.496), and 2h postmeal PG HbA1C (r=0.605), 1,5-AG (r=0.306), and 2h UMI (r=0.606). Two hour UMI and HbA1C (Japan Diabetes Society) were significant determinants of 2h postmeal PG. As HbA1C reflects PG excursion during the previous 1-3 months, UMI may be a useful marker for monitoring and management of postmeal hyperglycemia in type 2 diabetics. | |||||
DOI | ||||||
関連識別子 | 10.15369/sujms.24.33 | |||||
出版者 | ||||||
出版者 | Showa Medical Association and Showa University | |||||
ISSN | ||||||
収録物識別子 | 0915-6380 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |