WEKO3
アイテム
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The Effectiveness of Combined Medical Therapy and Hemodialysis for Hypercalcemia in Anaplastic Lymphoma Kinase-negative Anaplastic Large Cell Lymphoma
https://showa.repo.nii.ac.jp/records/642
https://showa.repo.nii.ac.jp/records/64258958df9-43ca-4ecf-898e-b47134018a0f
名前 / ファイル | ライセンス | アクション |
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S25_233.pdf (463.2 kB)
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Item type | 学内発行雑誌 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-11-17 | |||||
タイトル | ||||||
タイトル | The Effectiveness of Combined Medical Therapy and Hemodialysis for Hypercalcemia in Anaplastic Lymphoma Kinase-negative Anaplastic Large Cell Lymphoma | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ | departmental bulletin paper | |||||
著者 |
NAKAMURA, Yuya
× NAKAMURA, Yuya× INAGAKI, Masahiro× SHIMIZU, Tatsuo× FUJITA, Keiichiro× INOUE, Michiyasu× GOTOH, Hiromichi× TOMOYORI, Eiji× KONDO, Yasuyuki× TSUJI, Mayumi× OGUCHI, Katsuji× GOTO, Yoshikazu |
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書誌情報 |
The Showa University journal of medical sciences 巻 25, 号 3, p. 233-241, 発行日 2013-09 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A 71-year-old man with a right lower abdominal quadrant epithelial tumor developed gradually worsening lumbago and dysbasia. He became comatose and was admitted to our hospital. He had swelling of the left axillary lymph nodes and necrosis of the 4.0-cm diameter abdominal tumor, which infiltrated the subcutaneous tissues. He was hypercalcemic (16.7mg/dl), and had elevated levels of soluble interleukin-2 receptor (24,090U/ml) and parathyroid hormone-related protein (5.4pmol/l). Computerized tomography (CT) showed left axillary lymphadenopathy, splenomegaly, and a right abdominal-wall mass that was described as anaplastic large cell lymphoma upon pathology. Brain radiography and CT revealed multiple lesions infiltrating the cranium. Magnetic resonance imaging showed diffuse low signal intensity throughout the vertebral spine. The patient was diagnosed with anaplastic lymphoma kinase (ALK) -negative anaplastic large cell lymphoma with hypercalcemia. Fluid replacement and drug therapies including calcitonin had no effect on the hypercalcemia or the coma. The patient's serum calcium concentration decreased after hemodialysis (calcium dialysate concentration, 5mg/dl) and subsequent zoledronic acid hydrate therapy. His consciousness improved by the fifth day of treatment. This rare case of hypercalcemia in ALK-negative anaplastic large cell lymphoma improved with combined medical and hemodialysis therapy. | |||||
DOI | ||||||
関連識別子 | 10.15369/sujms.25.233 | |||||
出版者 | ||||||
出版者 | Showa University Society | |||||
ISSN | ||||||
収録物識別子 | 0915-6380 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |