| Item type |
学内発行雑誌 / Departmental Bulletin Paper(1) |
| 公開日 |
2017-12-07 |
| タイトル |
|
|
タイトル |
Usefulness of Intracardiac Local Ventricular Electrogram to Predict Responders in Patients Undergoing Cardiac Resynchronization Therapy |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ |
departmental bulletin paper |
| 著者 |
ONUMA, Yoshimasa
KAWAMURA, Mitsuharu
YOSHIKAWA, Kosuke
GOKAN, Toshihiko
OGAWA, Ko
NAKAMURA, Yuya
OCHI, Akinori
INOKUCHI, Koichiro
MUNETSUGU, Yumi
ONUKI, Tatsuya
ITO, Hiroyuki
WATANABE, Norikazu
KOBAYASHI, Youichi
|
| 書誌情報 |
The Showa University journal of medical sciences
巻 29,
号 2,
p. 131-139,
発行日 2017-06
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Cardiac resynchronization therapy (CRT) is a well-established, efficient strategy for medically-refractory congestive heart failure (HF) with ventricular conduction disturbances. However, about 30% of patients who undergo CRT do not receive any benefit. Therefore, we investigated the usefulness of the QRS-left ventricle (LV) interval for predicting responders during CRT implantation. This study included 66 patients who underwent CRT implantation. The definition of responder was a ≥15% reduction in LV end-systolic volume or ≥20% increase in LV ejection fraction. The QRS-LV interval was measured from the beginning of the body surface electrocardiogram QRS complex to the LV potential recorded by LV leads. We analyzed the correlations between the QRS-LV intervals and CRT responders, admission for HF and mortality. The patients were 67±12 years old, and their mean LV ejection fraction was 26.3%±8.3%. During follow-up (27.2±19.9 months), 27 patients were admitted for HF (40.1%), and 17 died (25.7%); the median QRS-LV interval was 103±33 msec. Patients were divided into 2 groups: wide QRS-LV (>103 msec), and narrow QRS-LV (<103 msec). The wide QRS-LV group had a lower mortality rate than the narrow QRS-LV group (77% vs. 53%, P<0.05). In patients with dilated cardiomyopathy, the QRS-LV interval was significantly wider in responders, compared to non-responders (112±9.2 vs. 80.0±10 msec, P<0.05). The QRS-LV interval did not correlate with CRT responders or admission for HF. The mortality rate was lower in patients with wide QRS-LV intervals, compared to narrow QRS-LV intervals. Furthermore, a wide QRS-LV interval might be a predictor for CRT responders in patients with dilated cardiomyopathy. |
| DOI |
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|
|
関連識別子 |
10.15369/sujms.29.131 |
| 出版者 |
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|
出版者 |
Showa University Society |
| ISSN |
|
|
収録物識別子 |
0915-6380 |
| 著者版フラグ |
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|
出版タイプ |
VoR |
S29_131.pdf (218.1 kB)
