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Genotypic characterization Escherichia coli strains from Japan producing AmpC beta-lactamase
https://showa.repo.nii.ac.jp/records/4159
https://showa.repo.nii.ac.jp/records/41599d17cb30-40a2-417c-b8a2-3209e391c75c
名前 / ファイル | ライセンス | アクション |
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S34_183.pdf (363.6 kB)
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Item type | 学内発行雑誌 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2023-04-07 | |||||
タイトル | ||||||
タイトル | Genotypic characterization Escherichia coli strains from Japan producing AmpC beta-lactamase | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ | departmental bulletin paper | |||||
著者 |
YAMOCHI, Tadanori
× YAMOCHI, Tadanori× YOSHIDA, Katsuhiko× OHIRA, Yasuyuki× OTA, Hirotaka× YAMOCHI, Toshiko× TAKIMOTO, Masafumi× TOKIMATSU, Issei |
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書誌情報 |
The Showa University journal of medical sciences 巻 34, 号 4, p. 183-190, 発行日 2022-12 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | AmpC is a class C Ambler β-lactamase that confers resistance to cephamycins. Globally reported AmpC-producing Enterobacterales are clinically important due to their therapeutic restrictions and epidemiology. Between April 2021 and May 2021, an outbreak of AmpC beta-lactamase-producing Escherichia coli occurred at Showa University Hospital. Because of this outbreak, plasmid typing, enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) analysis, conjugation experiments, and pulsed-field gel electrophoresis (PFGE) were performed to study the molecular epidemiological characteristics of these E. coli strains. ERIC-PCR and conjugation experiments detected IncFrepB+, IncFIA+, and IncFIB+ multiple-replicon conjugative plasmids carrying the AmpC gene (blaDHA-1). Five of eleven isolates showed the same PFGE banding pattern in the XbaI-digested genomic DNA, whereas the remaining six strains displayed minor variants. These data highlight the need for improvements to infection control and surveillance measures to prevent the spread of blaDHA-1-carrying E. coli strains. | |||||
DOI | ||||||
関連識別子 | 10.15369/sujms.34.183 | |||||
出版者 | ||||||
出版者 | Showa University Society | |||||
ISSN | ||||||
収録物識別子 | 2185-0968 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |