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Ordinary Autonomic Unbalance Can Reflect Diagnosis of Neurally Mediated Reflex Syncope
https://showa.repo.nii.ac.jp/records/627
https://showa.repo.nii.ac.jp/records/627af6e2745-d31a-4cb1-a2e0-7f061662bc20
名前 / ファイル | ライセンス | アクション |
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S26_85.pdf (299.0 kB)
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Item type | 学内発行雑誌 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-12-15 | |||||
タイトル | ||||||
タイトル | Ordinary Autonomic Unbalance Can Reflect Diagnosis of Neurally Mediated Reflex Syncope | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ | departmental bulletin paper | |||||
著者 |
ONISHI, Yoshimi
× ONISHI, Yoshimi× MINOURA, Yoshino× OCHI, Akinori× INOKUCHI, Kouichirou× CHIBA, Yuta× KAWASAKI, Shirou× MUNETSUGU, Yumi× ONUMA, Yoshimasa× KIKUCHI, Miwa× ONUKI, Tatsuya× ITO, Hiroyuki× MIYOSHI, Fumito× WATANABE, Norikazu× ADACHI, Taro× ASANO, Taku× TANNO, Kaoru× KOBAYASHI, Youichi |
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書誌情報 |
The Showa University journal of medical sciences 巻 26, 号 1, p. 85-93, 発行日 2014-03 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: In the present study we investigated autonomic dysfunction using hemodynamics and analysis of heart rate variability (HRV) following ambulatory blood pressure monitoring (APBM) in patients with neurally mediated reflex syncope (NMRS). In addition, we evaluated the usefulness of ABPM for diagnosing NMRS. Methods: In all, 88 consecutive patients with syncope and 12 controls (Group C) were subjected to a head-up tilt (HUT) test (80°, 30 min). If no syncope or presyncope occurred, the HUT test was repeated in the patient group following drug loading (ATP, isoproterenol, and/or isosorbide dinitrate). Results: Forty patients had a positive HUT test, with or without drug loading (Group P) ; the HUT test was negative in 48 patients, even after drug loading. Average daytime systolic and diastolic blood pressure (SBP and DBP, respectively) was significantly lower in Group P than in Group C (P = 0.042 and P = 0.047, respectively). The average standard deviation of SBP at night (SD-SBPNight) was significantly higher in Group P than in Group C (P = 0.004). HRV analysis revealed a significantly higher daytime high-frequency component in Group P than in Group C (P = 0.041). Conclusion: The results of the present study suggest that lower daytime blood pressure and a larger SD-SBPNight, as determined by ABPM, are associated with vagal nerve hyperactivity and sympathetic hypoactivity in patients with NMRS. Thus, an inadequate circadian rhythm in blood pressure variation, as identified by ABPM, may be useful for the diagnosis of NMRS. | |||||
DOI | ||||||
関連識別子 | 10.15369/sujms.26.85 | |||||
出版者 | ||||||
出版者 | Showa University Society | |||||
ISSN | ||||||
収録物識別子 | 0915-6380 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |