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  1. 学内発行雑誌
  2. The Showa University journal of medical sciences
  3. Vol.29(2017)
  4. No.2

Usefulness of Intracardiac Local Ventricular Electrogram to Predict Responders in Patients Undergoing Cardiac Resynchronization Therapy

https://showa.repo.nii.ac.jp/records/514
https://showa.repo.nii.ac.jp/records/514
a3e466f4-c46b-4abc-adf5-3cfd947d223a
名前 / ファイル ライセンス アクション
S29_131.pdf S29_131.pdf (218.1 kB)
Item type 学内発行雑誌 / Departmental Bulletin Paper(1)
公開日 2017-12-07
タイトル
タイトル Usefulness of Intracardiac Local Ventricular Electrogram to Predict Responders in Patients Undergoing Cardiac Resynchronization Therapy
言語 en
言語
言語 eng
資源タイプ
資源タイプ departmental bulletin paper
著者 ONUMA, Yoshimasa

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ONUMA, Yoshimasa

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KAWAMURA, Mitsuharu

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KAWAMURA, Mitsuharu

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YOSHIKAWA, Kosuke

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YOSHIKAWA, Kosuke

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GOKAN, Toshihiko

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GOKAN, Toshihiko

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OGAWA, Ko

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OGAWA, Ko

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NAKAMURA, Yuya

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NAKAMURA, Yuya

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OCHI, Akinori

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OCHI, Akinori

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INOKUCHI, Koichiro

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INOKUCHI, Koichiro

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MUNETSUGU, Yumi

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MUNETSUGU, Yumi

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ONUKI, Tatsuya

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ONUKI, Tatsuya

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ITO, Hiroyuki

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ITO, Hiroyuki

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WATANABE, Norikazu

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WATANABE, Norikazu

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KOBAYASHI, Youichi

× KOBAYASHI, Youichi

KOBAYASHI, Youichi

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書誌情報 The Showa University journal of medical sciences

巻 29, 号 2, p. 131-139, 発行日 2017-06
抄録
内容記述タイプ Abstract
内容記述 Cardiac resynchronization therapy (CRT) is a well-established, efficient strategy for medically-refractory congestive heart failure (HF) with ventricular conduction disturbances. However, about 30% of patients who undergo CRT do not receive any benefit. Therefore, we investigated the usefulness of the QRS-left ventricle (LV) interval for predicting responders during CRT implantation. This study included 66 patients who underwent CRT implantation. The definition of responder was a ≥15% reduction in LV end-systolic volume or ≥20% increase in LV ejection fraction. The QRS-LV interval was measured from the beginning of the body surface electrocardiogram QRS complex to the LV potential recorded by LV leads. We analyzed the correlations between the QRS-LV intervals and CRT responders, admission for HF and mortality. The patients were 67±12 years old, and their mean LV ejection fraction was 26.3%±8.3%. During follow-up (27.2±19.9 months), 27 patients were admitted for HF (40.1%), and 17 died (25.7%); the median QRS-LV interval was 103±33 msec. Patients were divided into 2 groups: wide QRS-LV (>103 msec), and narrow QRS-LV (<103 msec). The wide QRS-LV group had a lower mortality rate than the narrow QRS-LV group (77% vs. 53%, P<0.05). In patients with dilated cardiomyopathy, the QRS-LV interval was significantly wider in responders, compared to non-responders (112±9.2 vs. 80.0±10 msec, P<0.05). The QRS-LV interval did not correlate with CRT responders or admission for HF. The mortality rate was lower in patients with wide QRS-LV intervals, compared to narrow QRS-LV intervals. Furthermore, a wide QRS-LV interval might be a predictor for CRT responders in patients with dilated cardiomyopathy.
DOI
関連タイプ isIdenticalTo
関連識別子 10.15369/sujms.29.131
出版者
出版者 Showa University Society
ISSN
収録物識別子タイプ ISSN
収録物識別子 0915-6380
出版タイプ
出版タイプ VoR
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