| Item type |
学内発行雑誌 / Departmental Bulletin Paper(1) |
| 公開日 |
2020-06-01 |
| タイトル |
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|
タイトル |
Epicardial Adipose Tissue in the Right Atrium Is Associated with Progression of Atrial Fibrillation and Recurrence after Pulmonary Vein Catheter Ablation in Patients with Atrial Fibrillation |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ |
departmental bulletin paper |
| 著者 |
TANISAWA, Hiroki
AKUTSU, Yasushi
ITO, Hiroyuki
NOMURA, Kosuke
SEKIMOTO, Teruo
KANEKO, Kyoichi
KODAMA, Yusuke
ARAI, Ken
GOKAN, Toshihiko
ONISHI, Yoshimi
OCHI, Akinori
MUNETSUGU, Yumi
ONUKI, Tatsuya
OHGIYA, Yoshimitsu
MATSUMOTO, Hidenari
KAWAMURA, Mitsuharu
SHINKE, Toshiro
|
| 書誌情報 |
The Showa University journal of medical sciences
巻 32,
号 1,
p. 11-24,
発行日 2020-04
|
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
An increase in epicardial adipose tissue（EAT）in the left atrium（LA）predicts the progression of atrial fibrillation（AF）and AF recurrence after pulmonary vein catheter ablation（CA）. We hypothesized that EAT in the right atrium（RA）is also associated with the progression of AF and post-CA AF recurrence. Using 128-slice multidetector computed tomography, EAT volume and atrial volume were measured 3-dimensionally before CA in 68 patients who had proven AF（paroxysmal AF, 42; persistent AF, 26; mean age, 65±11 years; 42.6％ female）with successful CA and 21 volunteers with sinus rhythm（age, 63±13 years; 52.3％ female）. In both atria, EAT and atrial volumes were largest in patients with persistent AF, followed, in order, by those with paroxysmal AF, and then healthy volunteers（P＜0.001）. Increased EAT and atrial volumes in both atria predicted persistent AF（P＜0.001）. Fifteen patients had AF recurrence（22.1％）during the 2-year period after CA. Increased EAT volume in both atria were independent predictors for AF recurrence, and a RA EAT volume≥6.2ml was an independent predictor, with a hazard ratio of 5.47（95％ confidence interval, 1.2-24.3; P=0.03）. The combination of EAT and atrial volume in both atria was a more powerful independent prognostic factor, with a hazard ratio of 4.8（95％ confidence interval, 1.7-3.7; P=0.003）, and a sensitivity of 60％ in 9 of 15 patients, and specificity of 81.1％ in 43 of 53 patients,（P=0.003）. RA EAT is associated with the progression of AF and post-CA AF recurrence. |
| DOI |
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関連タイプ |
isIdenticalTo |
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関連識別子 |
10.15369/sujms.32.11 |
| 出版者 |
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出版者 |
Showa University Society |
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2185-0968 |
| 出版タイプ |
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出版タイプ |
VoR |
S32_11.pdf (563.5 kB)
