| Item type |
学内発行雑誌 / Departmental Bulletin Paper(1) |
| 公開日 |
2020-06-01 |
| タイトル |
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|
タイトル |
The Surgical Benefits of Repeat Hepatectomy for Colorectal Liver Metastasis |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ |
departmental bulletin paper |
| 著者 |
KUSANO, Tomokazu
AOKI, Takeshi
YAMAZAKI, Tatsuya
HIRAI, Takashi
TOMIOKA, Koudai
SHIBATA, Hideki
WADA, Yuusuke
HAKOZAKI, Tomoki
TASHIRO, Yoshihiko
NOGAKI, Kouji
MATSUDA, Kazuhiro
YAMADA, Kousuke
KOIZUMI, Tomotake
MITAMURA, Keitaro
FUJIMORI, Akira
KOIKE, Reiko
ENAMI, Yuta
MURAKAMI, Masahiko
|
| 書誌情報 |
The Showa University journal of medical sciences
巻 31,
号 4,
p. 355-364,
発行日 2019-12
|
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
The most common site of distant metastasis from colorectal cancer is the liver, and hepatectomy presents the best curative treatment for recurrence of colorectal liver metastasis （CRLM）. This study aimed to identify factors of prognostic value for repeat hepatectomy for CRLM and to determine whether a third such procedure could similarly produce favourable outcomes for CRLM. We analyzed data for 161 patients in our department with colorectal metastasis. Of these, 22 patients underwent repeat hepatectomy for recurrent metastasis, with 16 undergoing a second hepatectomy and 6 a third hepatectomy. We analyzed patient characteristics, tumor status, operation-related variables, and short- and long-term outcomes. Univariate analysis for repeat hepatectomy identified the following five prognostic risk factors: T factor （＞SE） of the primary cancer, number of tumors involved in the initial hepatectomy （＞5）, interval from first to second hepatectomy （＜1year）, number of tumors involved in second hepatectomy （＞3）, and post-operation time （＞30days）. By multivariate analysis, T factor （＞SE） of the primary cancer, number of tumors in the initial hepatectomy （＞5）, and number of tumors in the second hepatectomy （＞3） were independently associated with a worse survival after surgery for CRLM. Although surgical outcomes of the third hepatectomy were not compared with those of the first and second hepatectomy, there were no obvious differences, nor did the 1-, 3-, and 5-year survival rates differ significantly among the three groups. Repeat hepatectomy for CRLM could improve long-term survival. In addition, patients undergoing a third hepatectomy showed a similar survival benefit to those having one or two resections. |
| DOI |
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関連識別子 |
10.15369/sujms.31.355 |
| 出版者 |
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|
出版者 |
Showa University Society |
| ISSN |
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収録物識別子 |
0915-6380 |
| 出版タイプ |
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出版タイプ |
VoR |
S31_355.pdf (92.8 kB)
